Eukaryotic Transcription Factors

Eukaryotic Transcription Factors by Professor David Latchman is an essential work for readers seeking to understand the modes of action of the ostensibly bewildering assortment of control proteins, which can prove challenging both to those familiar and unfamiliar with molecular genetics. Transcription factors, or control proteins, govern the gene protein production process, ensuring that they are made in the right place at the right time. The book outlines the major families of eukaryotic transcription factors while describing how they activate and repress eukaryotic genes. It explains the connection between transcription factors’ structure and function, and it underscores these factors’ importance in the development, differentiation, and transformation of eukaryotic cells. Furthermore, it summarises the principles of the methods used to study transcription factors in vivo and in vitro.

In the fifth edition of this book, Professor David Latchman adds more than 60 new explanatory images, a section on small inhibitory RNAs and their impact on transcription regulation, a new section on the therapeutic application of transcription factors, and specific emphasis on the way transcription factors regulate chromatic structure and transcriptional elongation.