Written by David Latchman
Gene Control describes the way gene expression is controlled in eukaryotes while offering a review and summary that condenses the primary literature on the subject into an easily accessible format. The book is divided into two parts. The first, which consists of three chapters, deals with the fundamental processes of gene control pertaining to chromatin structure, transcription, and post-transcription.
It describes the basic process and then the way that process helps control gene expression. The second elaborates upon gene control in specific biological processes. Specifically, it addresses the importance of gene control in cellular signalling processes and normal embryonic development while discussing the critical roles of gene-regulatory processes in the specification of differentiated cell types, such as muscle cells and neurons. In addition, it discusses the implications of errors in gene control as well as the relationship between the mistaken regulation of genes and the preponderance of human diseases, particularly cancer.
It also explains therapies that can target specific levels of gene control. The book is relevant to everyone from biological science students to scientists and clinicians studying the regulation of genes in health and disease.